Project Description
Coming Soon
Experience
- Comparative Analysis of Arylsulfatase and Its Mutants Pharmacological Chaperone Search for Arylsulfatase A Mutants, Project coordinator: Prof. Kutlu Ülgen, Tubitak 115S208, October 2015-August 2017.
- Computational Analysis of the Binding Modes of GW4869 to nSMase – in collaboration with Dr. Yusuf Hannun, 2016-2017.
Publications
- Fatma Gizem Avci, Fatma Ece Altinisik, Ipek Karacan, Duygu Senturk Karagoz, Serhat Ersahin, Ayse Eren, Didem Vardar Ulu, Elif Ozkirimli, Nihat Sayar, E., Berna Sariyar Akbulut, Targeting a hidden site on class A beta-lactamases, In review, 2018
Conference Presentations
- Eren,A Ölmez, E. Ö., Ülgen, K., “Comparative Analysis of Arylsulfatase A and Its Mutants”, 3rd International BAU Drug Design Congress, 1-3 October 2015, İstanbul - Turkey.
- Eren,A Ölmez, E. Ö., Ülgen, K., “Arylsulfatase A and Its Mutants: In the Light of Pharmacological Chaperone Search”, 4th International BAU Drug Design Congress, 13-15 October 2016, İstanbul - Turkey.
- Eren, A., Budak, M., Ölmez, E. Ö., Ülgen, K., ““Insights into the Effects of the Mutations of Arylsulfatase A on Its Structure Using Molecular Dynamic Simulations”, 8th International Ceramide Conference (iCC8) jointly with the 11th SLC meeting, 6- 10 May 2015, Çeşme - Turkey.
- Eren, A., Budak, M., Ölmez, E. Ö., Ülgen, K., “The Effects of the Mutations of Arylsulfatase A on Its Structure and Function”, Biophysical Society Meeting: Modeling of Biomolecular Systems Interactions, Dynamics, and Allostery: Bridging Experiments and Computations, 10-14 September 2014, İstanbul - Turkey.
- Eren, A., Ölmez, E. Ö., Ülgen, K., “Targeting Arylsulfatase A: Effect of Mutations on Mechanism and Dynamics”, Glycolipid & Sphingolipid Biology Gordon Research Conference, 6-11 March, 2016, Barga - Italy
- Eren, A., Ölmez, E. Ö., Ülgen, K., “Identification of the Effects of Mutations on the Stability and Function of Arylsulfatase A and Chaperone Search”, EMBO Conference: Chemical Biology, 31 August- 3 September 2016, Heidelberg-Germany.
Education
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